genomics

DNA-DETR: Sequence representation matters in object detection for functional genomic elements

Object detection has revolutionized multiple domains by enabling models to jointly classify and localize targets within data. Yet, its potential in genomic sequence analysis remains largely unexplored. Here, we introduce DNA-DETR, an adaptation of …

Short human eccDNAs are predictable from sequences

Ubiquitous presence of short extrachromosomal circular DNAs (eccDNAs) in eukaryotic cells has perplexed generations of biologists. Their widespread origins in the genome lacking apparent specificity led some studies to conclude their formation as …